There are a number of factors that can have an Impact on the successful development of a Multimedia E Learning System.The must also be dedicated online support available at all the times Lack of easy access: The multimedia contents developed must be easily accessible to all the people intended to use the system.The multimedia content must not also have an inconsistent look and feel and the guidelines to follow the content must be defined.An initial check on whether students are ready to accept the multimedia content must be conducted.The Interactions were classified by Moore, 1989 as student-content, student instructor, Madhukar in 2002 pointed out some of the negative influences of using internet as a medium of e learning. Other  than the factors established by research mentioned above, there are some organizational factors that may result in the failure of multimedia e learning systems: a.) Inadequate planning: The objectives of any online e course can't be achieved if there isn't any specific plan regarding the development and distribution of the course.Papp in 2000 identified intellectual property, suitability of course content, building e learning course, suitability of e learning course and measuring the success of e learning courses as critical success factors for any e learning system.Online tools also enhance the interaction capabilities of an E Learning (Newberry, 2005).Newberry, 2008 says that quality of interactions is as important as the quality of content of an online E Learning.