1.Mango Mango is classified a level I causation, which is highly probable of having an interaction if consumed in large amounts with warfarin The exact interaction mechanism is unknown, but may be related to the vitamin A content(inhibit CYP2C19 enzymes).Foods Causing Inhibition: High Vitamin-K Containing Foods High Vitamin-K containing foods are classified a level 1 causation, which are highly probable of causing a lowered INR or clotting event when consumed with warfarin.Grapefruit juice Grapefruit juice is a well-known inhibitor of cytochrome P450 (CYP) liver enzymes, primarily CYP3A4, CYP1A2 and CYP2A6.2.