Leflunomide was purchased from Qingdao Franken Biochem
Co. (Qingdao, China).Fetal bovine serum (FBS),
(Dulbecco's Modified Eagle Medium) (DMEM), trypsin/EDTA,
and Penicillin streptomycin, were purchased from Lonza
company, Switzerland.PeceolVR
(glyceryl monooleate) was
kindly provided of by Gattefosse (Lyon, France).PoloxamerVR
407 was purchased from BASF chemical company
(Ludwigshafen, Germany).Oleic acid was bought from El-
Nasr Pharmaceutical (Cairo, Egypt).All other chemicals were of analyt-
ical grade.