Recent Advances 1.Drugs like pembrolizumab (Keytruda) and nivolumab (Opdivo) work by blocking the PD 1/PD-L1 pathway, preventing cancer cells from evading immune detection.Combination Therapies: Combining checkpoint inhibitors with other treatments, such as chemotherapy or radiation, has shown promise in improving patient outcomes.Immune Checkpoint Inhibitors: PD-1/PD-L1 and CTLA-4 Inhibitors: These have been some of the most groundbreaking advances in immunotherapy.