Clinical Significance As most cases of PDPH's resolve spontaneously within 7 to 10 days, some patients may opt for conservative treatment rather than EBP.It is administered as 500 mg sodium caffeine benzoate in 1000 mL of NS or LR over 1 to 2 hours.Also, those patients that are extremely symptomatic (some cephalgia even when supine and cannot tolerate any degree of upright positioning, tearful or crying at rest, photophobia) will likely consent to EBP with or without conservative treatment.A patient who chooses conservative therapy should keep well hydrated and consume caffeine-containing beverages and oral analgesics as necessary at home.