Definition of pharmacodynamic:
It means the action of a drug on the body, including receptor interactions, dose-response phenomena, and
mechanisms of therapeutic and toxic action.Physically: e.g. by adsorption (kaolin and pectin in diarrhea), stool softners in constipation (e.g
lactulose), osmosis (osmotic diuretics), etc
2.Example: Aspirin
Action of aspirin: block prostaglandin synthesis by inhibiting COX-enzymes.Drugs act by:
A. Receptor-binding way (conventional mechanism): most drugs act on receptors.Chemically: e.g. treatment of hyperacidity by NaHCO3 (neutralization of HCL).3.4.5.6.7.