When a medication is crushed, it may become more vulnerable to contamination by bacteria or other substances.Changes in the release of the active ingredient.Additionally, it destroys the tablet coating, making the crushed powder more susceptible to environmental factors, such as moisture from the air, that can hasten drug degradation, some tablets are long-acting formulations that are slowly released into the body and can last for up to 24 hours.crushing tablets or opening capsules that are taken orally, when it is not prescribed, can affect the efficacy of a treatment, or even cause an adverse event.Modification of absorption (enteric-coated tablets).Which tablets should never be crushed?Disadvantages:
1.2.3.4.5.6.1.2.3.4.5.6.