The syndrome of hepatocellular insufficiency, also known as hepatic coma, is a condition characterized by the inability of the liver to perform its normal metabolic functions.Other symptoms may include jaundice, ascites (fluid accumulation in the abdomen), and gastrointestinal bleeding.This may include medications to reduce ammonia levels in the blood, dietary changes, and in severe cases, liver transplantation.Signs and symptoms of hepatic coma may include confusion, disorientation, slurred speech, tremors, seizures, and coma.Treatment for hepatic coma includes addressing the underlying cause of the liver dysfunction and managing symptoms.