Morton's Neuroma Kilmartin and Wallace167 found that orthotic intervention did not improve symptoms of Morton's neuroma.Twenty-three individuals with pain of the third and fourth intermetatarsal space, aggravated by exercise and relieved by rest, were randomly assigned to two groups, with no consideration of foot type.Those in the supination group wore a Cobra orthosis with a thicker medial heel and arch filler.Those in the pronation group wore a reverse Cobra orthosis with a thicker lateral heel.