trend with the Hammett substituent constants, but the logarithms of the rate
constants do not give straight lines as a function of the substituent constants,
because the kOHs are controlled by both the chemical reactivity and the diffusion.r PhXOH d16TH
In aromatic compounds, electron-donating substituent directs
OH into the orthoand para-positions; in the case of the electron withdrawing substituents, metaaddition is preferred [45, 46].In the case of phenol, ipso-, ortho-, meta- and para-additions take place
with probabilities of 0.08, 0.50, 0.08 and 0.34, respectively8), however, show
linear correlation with rp for monosubstituted benzenes (Fig.