Implementing nutritional guidelines: a public health perspective An often-overlooked yet important limitation in nutritional research and in the development of guidelines is the study of individual dietary patterns as determined by food systems, food environment and the availability and affordability of healthy foods.From a research perspective, Mediterranean cities present unique characteristics in terms of diversity of small food stores and public markets, whose accessibility is paramount if we want to effectively stir dietary and lifestyle habits toward healthier profiles [77,78] (Fig.Within the Heart Healthy Hoods (HHH) project (https:// hhhproject.eu, funded by the European Research Council), researchers are studying the association between the Mediterranean food environment, adherence to the Mediterranean diet, and related chronic diseases [78,79].Different urban characteristics relate to heart disease and its risk factors including dietary patterns, hypertension, diabetes and obesity [76]. 1).