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Advantages and Disadvantages The primary advantage of ISE is that it is a non-destructive technique and can be carried out without the consumption of the analyte.Furthermore, ion detection can be inaccurate if the solution is concentrated because the mobility of ions is decreased due to the inter-ionic interactions, which lower the concentration near the membrane.Consequently, the passage of unwanted ions affects the measured potential.Moreover, the response time is in seconds to minutes, making this method useful for industrial applications.

Advantages and Disadvantages
The primary advantage of ISE is that it is a non-destructive technique and can be carried out without the consumption of the analyte. The analysis is also non-contaminating and provides results over a short response time. This enables the monitoring of ion activity with time. Moreover, the response time is in seconds to minutes, making this method useful for industrial applications. The method is not affected by the turbidity or color of the samples and the setup is easy to operate while being inexpensive.

ISE has its own drawbacks. For one, the selective membrane may allow more than one ion since no membrane permits only one ion to pass. Consequently, the passage of unwanted ions affects the measured potential. Since ISE is dependent on its membrane, its use may be limited to one ion only. Furthermore, ion detection can be inaccurate if the solution is concentrated because the mobility of ions is decreased due to the inter-ionic interactions, which lower the concentration near the membrane.