خدمة تلخيص النصوص العربية أونلاين،قم بتلخيص نصوصك بضغطة واحدة من خلال هذه الخدمة
Abstract
7
, Nicola Veronese
8,9
and Brendon Stubbs
10,11,12
Background: Depression in tuberculosis increases the risk for adverse health outcomes. However, little is known
about comorbid depression and tuberculosis in the general population. Thus, we assessed the association between
depression and tuberculosis, and the decrements in health status associated with this comorbidity in 48 low- and
middle-income countries.
Methods: Cross-sectional, community-based data from the World Health Survey on 242,952 individuals aged ≥ 18 years
were analyzed. Based on the World Mental Health Survey version of the Composite International Diagnostic Interview,
past 12-month depression was categorized into depressive episode, brief depressive episode, subsyndromal depression,
and no depression. Health status across six domains (cognition, interpersonal activities, sleep/energy, self-care, mobility,
pain/discomfort) was assessed. Multivariable logistic and linear regression analyses were performed to assess the
associations.
Results: The prevalence of depressive episode among those with and without tuberculosis was 23.7% and 6.8%,
respectively (P < 0.001). Tuberculosis was associated with a 1.98 (95% CI 1.47–2.67), 1.75 (95% CI 1.26–2.42), and 3.68
(95% CI 3.01–4.50) times higher odds for subsyndromal depression, brief depressive episode, and depressive episode,
respectively. Depressive episode co-occurring with tuberculosis was associated with significantly worse health status
across all six domains compared to tuberculosis alone. Interaction analysis showed that depression significantly
amplifies the association between TB and difficulties in self-care but not in other health domains.
Conclusions: Depression is highly prevalent in adults with tuberculosis, and is associated with worse health status
compared to tuberculosis without depression. Public health efforts directed to the recognition and management of
depression in people with tuberculosis may lead to better outcomes.
Abstract
7
, Nicola Veronese
8,9
and Brendon Stubbs
10,11,12
Background: Depression in tuberculosis increases the risk for adverse health outcomes. However, little is known
about comorbid depression and tuberculosis in the general population. Thus, we assessed the association between
depression and tuberculosis, and the decrements in health status associated with this comorbidity in 48 low- and
middle-income countries.
Methods: Cross-sectional, community-based data from the World Health Survey on 242,952 individuals aged ≥ 18 years
were analyzed. Based on the World Mental Health Survey version of the Composite International Diagnostic Interview,
past 12-month depression was categorized into depressive episode, brief depressive episode, subsyndromal depression,
and no depression. Health status across six domains (cognition, interpersonal activities, sleep/energy, self-care, mobility,
pain/discomfort) was assessed. Multivariable logistic and linear regression analyses were performed to assess the
associations.
Results: The prevalence of depressive episode among those with and without tuberculosis was 23.7% and 6.8%,
respectively (P < 0.001). Tuberculosis was associated with a 1.98 (95% CI 1.47–2.67), 1.75 (95% CI 1.26–2.42), and 3.68
(95% CI 3.01–4.50) times higher odds for subsyndromal depression, brief depressive episode, and depressive episode,
respectively. Depressive episode co-occurring with tuberculosis was associated with significantly worse health status
across all six domains compared to tuberculosis alone. Interaction analysis showed that depression significantly
amplifies the association between TB and difficulties in self-care but not in other health domains.
Conclusions: Depression is highly prevalent in adults with tuberculosis, and is associated with worse health status
compared to tuberculosis without depression. Public health efforts directed to the recognition and management of
depression in people with tuberculosis may lead to better outcomes.
تلخيص النصوص العربية والإنجليزية اليا باستخدام الخوارزميات الإحصائية وترتيب وأهمية الجمل في النص
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