لخّصلي

Pharmacologic therapy: In coronary cardiogenic shock, the aims of vasoactive medication therapy are improved cardiac contractility, decreased preload and afterload, or stable heart rate.Sympathomimetic medications: increase cardiac output by mimicking the action of the sympathetic nervous system through vasoconstriction, resulting in increased preload, and by increasing myocardial contractility (inotropic action) or increasing the heart rate (chronotropic action).

Pharmacologic therapy: In coronary cardiogenic shock, the aims of
vasoactive medication therapy are improved cardiac contractility, decreased
preload and afterload, or stable heart rate.
• Because improving contractility and decreasing cardiac workload are
opposing pharmacologic actions, two classifications of medications may be
administered in combination: sympathomimetic agents and vasodilators.
Sympathomimetic medications: increase cardiac output by mimicking the
action of the sympathetic nervous system through vasoconstriction, resulting
in increased preload, and by increasing myocardial contractility (inotropic
action) or increasing the heart rate (chronotropic action).
Vasodilators: are used to decrease preload and afterload, thus reducing the
workload of the heart and the oxygen demand.
•Medications commonly combined to treat cardiogenic shock include
dobutamine, dopamine, and nitroglycerin In addition to medications,
appropriate fluid is necessary in treating cardiogenic shock.