Title: Lysosomal Storage Diseases: A Comprehensive Review Abstract: Lysosomal storage diseases (LSDs) encompass a diverse group of inherited metabolic disorders characterized by the accumulation of undegraded macromolecules within lysosomes.In summary, this report provides an in-depth exploration of lysosomal storage diseases, including their pathogenesis, clinical manifestations, diagnostic approaches, and current treatment strategies.Common manifestations include hepatosplenomegaly, skeletal abnormalities, neurological deterioration, and progressive organ dysfunction.1.2.3.4.5.6.7.8.