CCB are used for the management of angina, hypertension, dysrhythmias, and migraine prophylaxis.Hyperglycemia may occur because CCB inhibits insulin release Diagnosis: ECG, Cardiac markers, transcutaneous pacing, gastric lavage and activated charcoal.Treatment: Dopamine, normal saline for hypotension, glucagon IV, calcium chloride or calcium gluconate, ?- blockers and propranolol.CCB are rapidly emerging as one of the most lethal prescription drug ingestion.