According to the previous studies, there is no study
about the relation of serum level and RHL.In contrast, another study reject the
immunity enhancement by calcitriol injection after influenza vaccinationThe antimicrobial effect of vitamin D supplementation
has been explained in previous studies for viral disease
such as respiratory infections, HIV and hepatitis B .Some studies reported a lower level of in patients with
hepatitis B. They also proposed that high level of viral
load in these patients was related to vitamin D deficiency
; However, Jones G. et al. did not show any relation,
A study proposed that low serum level of vitamin D in
patients with hepatitis B might induce higher replication
level of hepatitis B virus .In a study INF-?alone in an animal
model .