Diamicron Themostcommonlyobserved side effect is low blood sugar(hypoglycaemia).Skin disorders Skin reactions have been reported such as: rash, redness, itching,hives, blisters, angioedema (rapid swelling of tissues such as eyelids, face, lips, mouth, tongue or throat that may result in breathing difficulty).Rash may progress to widespread blistering or peeling of the skin.This may cause: paleness, prolongedbleeding, pruising, sore throat, fever.