Fish and seafood constitute an important food component for a large number of the world population; they come after meat and poultry as major animal protein foods, where fish is considered a cheap source of protein.belong to the genus Vibrio which defined as Gram-negative, rod or curved rod-shaped coma shaped, they are motile (most of them having single polar flagellum), oxidase-positive except two species (V. metschnikovii and V. furnissi), catalase-positive, facultative anaerobes.In general, seafood comprises one of the fastest growing sources of food; billions of people throughout the world rely on fish as a primary source of protein (Sudha et al., 2012).However, increased seafood consumption comes with the potential risk of eating contaminated seafood with different contaminants.Vibrio (V.) spp.Vibrio spp.