The pharmaceutical industry has established categorization systems to help manage exposure and contamination risks.Most process handling for potent compounds is designed for closed operations to provide primary containment through the equipment, and secondary measures are taken in the design of heating, ventilation, and air conditioning (HVAC) systems and airlocks.As a result, many new facilities have implemented enhanced control measures for both a primary (where the product is exposed) and a secondary (where the product has been packaged in a nal form but has not received secondary packaging for nal shipment) containment.