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Major cellular functions performed by specialized cells
in the body are listed in Table 2–1. It is important to under
-
stand that the functions listed there can be performed by most
cells of the body; specialized cells have greatly expanded their
capacity for one or more of these functions during differentiation. Changes in cells’ microenvironments under normal
and pathologic conditions can cause the same cell type to have
variable features and activities. Cells that appear similar structurally often have different families of receptors for signaling
molecules such as hormones and extracellular matrix (ECM)
components, causing them to behave differently. For example,
because of their diverse arrays of receptors, breast fibroblasts
and uterine smooth muscle cells are exceptionally sensitive to
female sex hormones while most other fibroblasts and smooth
muscle cells are insensitive.
stand that the functions listed there can be performed by most
cells of the body; specialized cells have greatly expanded their
capacity for one or more of these functions during differentiation. Changes in cells’ microenvironments under normal
and pathologic conditions can cause the same cell type to have
variable features and activities. Cells that appear similar structurally often have different families of receptors for signaling
molecules such as hormones and extracellular matrix (ECM)
components, causing them to behave differently. For example,
because of their diverse arrays of receptors, breast fibroblasts
and uterine smooth muscle cells are exceptionally sensitive to
female sex hormones while most other fibroblasts and smooth
muscle cells are insensitive.
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