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Family history has long been known to be a risk factor for breast cancer.BRCA1 and BRCA2 are abnormal genes that, when inherited, markedly increase the risk of breast cancer to a lifetime risk estimated between 40 and 8S%.Both maternal and paternal relatives are important.First-degree relatives, (mother, sister, daughter) are most important in estimating risk.4
Family history has long been known to be a risk factor for breast cancer. Both maternal and paternal relatives are important. The risk is highest if the affected relative developed breast cancer at a young age, had cancer in both breasts, or if she is a close relative. First-degree relatives, (mother, sister, daughter) are most important in estimating risk. Several second degree relatives grandmother,aunt)with breast cancer may also increase risk. Breast cancer in a male increases the risk for all his close female relatives. BRCA1 and BRCA2 are abnormal genes that, when inherited, markedly increase the risk of breast cancer to a lifetime risk estimated between 40 and 8S%. Women who have the BRCA1 gene tend to develop breast cancer at an early age .
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