Lakhasly

Renal function, in nephrology, is an indication of the state of the kidney and its role in renal physiology.The most common cause of an elevated B.Urea( azotemia) is poor kidney function, although a serum creatinine level is a somewhat more specific measure of renal function .A greatly elevated BUN (>60 mg/dL) generally indicates a moderate-tosevere degree of renal failure.Kidney function tests is a number of clinical laboratory tests that measure the levels of substances normally regulated by the kidneys can help determine the cause and extent of kidney dysfunction.Creatinine clearance rate (CCr or CrCl) is the volume of blood plasma that is cleared of creatinine per unit time and is a useful measure for approximating the GFR.Normal human adult blood should contain between (15-40) mg/dl.

Renal function, in nephrology, is an indication of the state of the kidney and its role in
renal physiology. Glomerular filtration rate (GFR) describes the flow rate of filtered
fluid through the kidney. Creatinine clearance rate (CCr or CrCl) is the volume of
blood plasma that is cleared of creatinine per unit time and is a useful measure for
approximating the GFR. Both GFR and CCr may be accurately calculated by
comparative measurements of substances in the blood and urine.
Kidney function tests is a number of clinical laboratory tests that measure the levels of
substances normally regulated by the kidneys can help determine the cause and extent
of kidney dysfunction. These tests are done on urine samples, as well as on blood
samples.
Physiology:
The liver produces urea in the urea cycle as a waste product of the digestion of
protein. Normal human adult blood should contain between (15-40) mg/dl.
The most common cause of an elevated B.Urea( azotemia) is poor kidney function,
although a serum
creatinine level is a somewhat more specific measure of renal
function .A greatly elevated BUN (>60 mg/dL) generally indicates a moderate-tosevere degree of renal failure. Impaired renal excretion of urea may be due to
temporary conditions such as dehydration or shock, or may be due to either acute or
chronic disease of the kidneys themselves.
The blood urea nitrogen (BUN) test is a measure of the amount of nitrogen in the
blood in the form of urea, and a measurement of renal function. Urea is a substance
secreted by the liver, and removed from the blood by the kidneys