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Cancerous tumors are the foremost reason for morbidity and mortality, considering that millions of people are dying annually.Chemotherapeutic drugs show inadequate clinical effectiveness, due to the development of drug resistance during CT alongside the serious and life-threatening side effects, which increases the mortality rate in cancer patients.Breast cancer (BC) is categorized at the top of the most prevalent, while hepatocellular types carcinoma (HCC) is the fifth most widespread malignant tumor worldwide.
Cancerous tumors are the foremost reason for morbidity and mortality, considering that millions of people are dying annually. Breast cancer (BC) is categorized at the top of the most prevalent, while hepatocellular types carcinoma (HCC) is the fifth most widespread malignant tumor worldwide. Quite a lot of basic modalities are used to manage cancerous tumors, either alone or combined, including chemotherapy (CT) and radiotherapy (RT). However, the effectiveness and application of CT and RT are hindered by their serious side effects. Chemotherapeutic drugs show inadequate clinical effectiveness, due to the development of drug resistance during CT alongside the serious and life-threatening side effects, which increases the mortality rate in cancer patients. To deal with these problems, progress in new strategies is indispensable. Scientists continuously attempt to discover novel medications from natural phytoconstituents, or synthetic/semisynthetic organic or inorganic compounds. Radiosensitizers are agents that can drive tumor cells to be sensitive to radiation by enhancing the liberation of free radicals, thus forcing the cells toward apoptosis
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