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The diagnosis of lung cancer typically involves a combination of medical history evaluation, physical examination, imaging tests, and biopsy.Genetic Testing: Genetic testing of the tumor tissue may be performed to identify specific mutations or genetic alterations that can guide treatment decisions, especially for targeted therapies and immunotherapies.Histological Examination: The tissue samples obtained during the biopsy are examined by a pathologist to determine the type of lung cancer (e.g., NSCLC, SCLC) and its characteristics, such as tumor grade and genetic mutations.Imaging Tests: Imaging tests, such as chest X-rays, computed tomography (CT) scans, and positron emission tomography (PET) scans, are used to visualize the lungs and detect any abnormalities, such as tumors or suspicious nodules.During a biopsy, a sample of tissue is obtained from the lung tumor or nearby lymph nodes for examination under a microscope by a pathologist.Following diagnosis and staging, a multidisciplinary team of healthcare providers, including medical oncologists, radiation oncologists, and surgeons, will collaborate to develop a personalized treatment plan for the patient.Here's an overview of the diagnostic process:

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Original text

The diagnosis of lung cancer typically involves a combination of medical history evaluation, physical examination, imaging tests, and biopsy. Here's an overview of the diagnostic process:




  1. Medical History and Physical Examination: The doctor will ask about symptoms, risk factors, and any relevant medical history. A physical examination may also be performed to assess general health and detect any signs of lung cancer, such as abnormal lung sounds or enlarged lymph nodes.




  2. Imaging Tests: Imaging tests, such as chest X-rays, computed tomography (CT) scans, and positron emission tomography (PET) scans, are used to visualize the lungs and detect any abnormalities, such as tumors or suspicious nodules.




  3. Biopsy: If imaging tests suggest the presence of lung cancer, a biopsy is usually performed to confirm the diagnosis. During a biopsy, a sample of tissue is obtained from the lung tumor or nearby lymph nodes for examination under a microscope by a pathologist. Biopsy methods include:



    • Bronchoscopy: A thin, flexible tube with a camera (bronchoscope) is inserted through the mouth or nose into the airways to collect tissue samples.

    • Needle Biopsy: A needle is guided into the lung tumor using imaging techniques, such as CT or ultrasound, to obtain tissue samples.

    • Surgical Biopsy: In some cases, a surgical procedure, such as a thoracotomy or video-assisted thoracoscopic surgery (VATS), may be performed to remove a larger tissue sample for biopsy.




  4. Histological Examination: The tissue samples obtained during the biopsy are examined by a pathologist to determine the type of lung cancer (e.g., NSCLC, SCLC) and its characteristics, such as tumor grade and genetic mutations.




  5. Staging: Once lung cancer is diagnosed, further tests, such as additional imaging studies and sometimes blood tests, may be performed to determine the stage of the cancer. Staging helps determine the extent of the cancer's spread and guides treatment decisions.




  6. Genetic Testing: Genetic testing of the tumor tissue may be performed to identify specific mutations or genetic alterations that can guide treatment decisions, especially for targeted therapies and immunotherapies.




Following diagnosis and staging, a multidisciplinary team of healthcare providers, including medical oncologists, radiation oncologists, and surgeons, will collaborate to develop a personalized treatment plan for the patient.


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