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Chelation therapy recombines metals and allows the removal of excess or toxic substances.The combination of therapy of different chelating agents carries
both the beneficial effects on the liver and a more rapid removal of toxic metals from the liver.The significant amount of heavy metals was
excreted in the urine after a challenged dose of chelating agent, so it can thus be concluded from the
present study that MiADMSA TDS is a better treatment option than BD for chelation of heavy
metals in hepatitis c virus patients.The accessibility of new chelators' offerings new opportunities to the
clinician treating HCV patients with metals overload.
Chelation therapy recombines metals and allows the removal of excess or toxic substances. In
the world of increased metal exposure, chelation therapy is an important tool in fighting metal
storage disorders, but still the lack of large-scale clinical trials still raises controversy regarding its
clinical therapeutic benefit. The accessibility of new chelators’ offerings new opportunities to the
clinician treating HCV patients with metals overload. The significant amount of heavy metals was
excreted in the urine after a challenged dose of chelating agent, so it can thus be concluded from the
present study that MiADMSA TDS is a better treatment option than BD for chelation of heavy
metals in hepatitis c virus patients. The combination of therapy of different chelating agents carries
both the beneficial effects on the liver and a more rapid removal of toxic metals from the liver.
Future studies should support to determine the long-term success of chelating agents, the role of
several agents in patients with less severe iron overload, and the effectiveness and safety of new
combinations of these chelating agents. Further, newer therapeutic strategies should be explored that
may have a better therapeutic effect. Combination therapies with multiple chelating agents and/or
prescription antioxidants or nutraceuticals may be considered more critical as a key recommendation
for chelation therapy
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