Lakhasly

The advancement of medicine has reduced the global mortality rate; the older adult population continues to grow and is expected to reach 1 in 6 people by 2050 .Aging is a universal and irreversible biological process characterized by reduced defense mechanisms against the environment, loss of functional reserves, and a tendency for organs an apparatuses to atrophy . Age-related involutional physiological changes
underlying the natural aging process can promote the occurrence of oral pathologies in the elderly . Moreover, systemic diseases and conditions may affect oral health, and oral diseases can influence the course of systemi disorders. Such inter-relations are especially evident in elderly patients due to a higher prevalence of both systemic and oral diseases associated with the physiological effects of advancing age .
Age-related systemic conditions and diseases predisposing to adverse oral outcomes mainly comprise frailty (malnutrition, sarcopenia, osteopenia, disability, balance disorders, falls, etc.); various severe co-morbid states; Alzheimer’s and other forms of dementia;
Parkinson’s disease and other nervous system degenerative disorders; brain stroke sequelae with severe disability and dysphagia; and neoplastic disease statins . Consequently, the reduced autonomy in daily activities; cognitive impairment and behavioral symptoms
interfering with oral hygiene procedures; swallowing and chewing disorders subsequent to neurological vascular and degenerative diseases; and polypharmacotherapy potentially
responsible for xerostomia and other side effects affecting the oral cavity, may promote the occurrence of oral diseases in the elderly . As a counterpart, some oral diseases—more frequently odontogenic and periodontal acute or chronic infections—may also negatively impact certain systemic disorders, including cardiovascular diseases, diabetes mellitus, inflammatory and degenerative disorders, benign and malignant solid neoplasms, and respiratory infectious diseases . The interconnections between oral and systemic inflammatory status and microbiome, along with oral dysbiosis , have been proposed to potentially encourage—through direct and indirect mechanisms—the development and progression of such systemic disorders.
The most frequent oral conditions and disorders in older patients comprise, along with benign mucosal lesions and oral cancer, edentulism, caries, and periodontal disease . It is worth noting that an increased incidence of HPV-related oropharyngeal squamous
cell carcinoma has been recorded in White men > 65 years in the United States, with aconcurrent decrease in the smoking-associated form of disease . Fortunately, similar survival rates between ≤70 and >70 years of age have been recorded in patients undergoing chemoradiotherapy, or radiotherapy alone; nonetheless, these rates have been
improved by surgical approaches for elderly patients .
Tooth loss has been closely related to age, even though significant differences in prevalence between groups with different socio-cultural and economic statuses have been reported . Socioeconomic status, education, and especially tobacco use are known
to be risk factors for tooth loss in the elderly, which is nevertheless attributable in most cases to caries and periodontitis.
Dental caries is a chronic disease with multifactorial etiology involving the destruction of dental tissues, proceeding from the outer surface of the enamel toward the pulp. Agerelated changes in the enamel surface, facilitating the development of more extensive caries when exposed to acids compared to young individuals , and wear phenomena ,
may be responsible for a higher incidence of caries, both at the coronal and root level, in the elderly population. In detail, root caries appears to be much more frequent in the elderly than in the young. Indeed, while the prevalence of coronal enamel caries rises to the age of 40–50 years and then slightly decreases, root caries, which is generally less frequent,
gradually and continuously increases with higher peaks in advanced age, concurrent with gingival recession increasing with age .
Periodontitis is a chronic inflammatory disease of the tissues supporting the tooth with an infectious etiology . Its prevalence generally increases from 5% at age 15 to 80% at age 60 , and periodontal tissue destruction increases with increasing age (UN Decade of Healthy Ageing (who.int)). Several age-related diseases, such as diabetes
mellitus, osteoporosis, and blood disorders, also assume risk factors for periodontitis onset and progression . The high prevalence of periodontal disease in the elderly might be especially relevant, as the disease directly increases the risk of the onset of edentulism and complex rehabilitation needs , with potential sequelae on the patient’s nutrition,
general health, and quality of life .
Both dysbiotic diseases are etiologically related to biofilm accumulation and favored by the frequent decrease in salivary secretion, particularly in older adults with polypharmacy and poor oral hygiene practice , often coupled with scarce oral healthcare literacy and
reduced dental care. In an elderly person, the co-existence of minor and major disabling diseases, multi-drug therapies, physical infirmities, and mental disorders may induce them to consider dental treatments less relevant, thus, allowing further deterioration of oral, periodontal, and dental conditions, with possible effects also at the systemic level. In addition, older subjects commonly still ignore the importance of oral health and generally attend dental services less due to several obstacles, including a loss of independence, the onset of disabling conditions, or cognitive and motor deficits.
Moreover, older adults suffering from depression and dementia may not obtain access to dental care due to complicated dental treatment provisions in a supine position.
Furthermore, the COVID-19 pandemic has unfortunately enhanced gaps and disparities in dental care services, conceivably linked to the recognition of older age and age-related co-morbidities, also including periodontitis and medications as major risk factors for COVID-19 onset and severity , and increasing the detection of oral coinfections in SARS-CoV-2 positive adult subjects and oral adverse reactions following vaccination .
Concomitantly, in recent decades, thanks to the improvement in socioeconomic conditions, nutrition, health education, and oral hygiene maneuvers, a reduced prevalence of total edentulism has fortunately been recorded both in Europe and the US . The progressive decline of edentulism has consequently led to an increasing number of natural teeth in elderly individuals and, thus, to a raised demand for conservative care, on the
one side, and, coupled with the increased prevalence of periodontitis, to a higher need for periodontal treatments, on the other side.
Therefore, it appears evident that geriatric dentistry should accurately focus on oral age-related conditions and diseases, adapting dental practice and home care instructions to the elderly’s oral and systemic specific needs and providing multidisciplinary solutions and treatment. Elderly oral health home care may benefit from manual toothbrushes with wide-handle grips, electric toothbrushes, and floss-holding devices; moreover, primary care physicians may aid in educating older patients in maintaining good oral health, assessing risk factors through proper oral examination, and identifying physiological oral age-related changes from abnormal conditions and pathologies at an early stage, as well as referring patients to a dentist if needed.