Online English Summarizer tool, free and accurate!
The complete sequencing of the coding region and
intron/exon junction TMPRSS6 gene (Reference Sequence
NM_153609.3) was performed among 98 Saudi females in
the current study.To
the best of our knowledge, there is no previous study that
identified this mutation in any population or database;
therefore, it is a novel variant.Thirty-three variants
were previously reported in the Single Nucleotide Polymorphism Database (dbSNP) and eight variants were novel (1
located in 50 UTR, 2 in introns and 5 were within exons).The size of the sequenced DNA was approximately
664 kb. Forty-one variants were detected; two variants
were found in 50 UTR, 17 variants were located in introns,
and 22 were variants located in exons.About 6.8 kb was sequenced for each participant.
The complete sequencing of the coding region and
intron/exon junction TMPRSS6 gene (Reference Sequence
NM_153609.3) was performed among 98 Saudi females in
the current study. About 6.8 kb was sequenced for each participant. The size of the sequenced DNA was approximately
664 kb. Forty-one variants were detected; two variants
were found in 50 UTR, 17 variants were located in introns,
and 22 were variants located in exons. Thirty-three variants
were previously reported in the Single Nucleotide Polymorphism Database (dbSNP) and eight variants were novel (1
located in 50 UTR, 2 in introns and 5 were within exons).
No variants were found in exons 4, 6, 8, 10, and 15. To
the best of our knowledge, there has been no previous
report that identified g.-2 T > G variants in any population
or database. Therefore, it is considered a novel variant in
our study. This polymorphism could affect the gene expression. In exon 2 G > A nucleotide, a substitution at position
219 (c.219G > A) was detected. This base substitution generates nonsense mutation, where tryptophan changed to a premature stop codon (p.W73X). This genetic variation
was observed in one of IDA and one of IRIDA patients in a
heterozygous state. These two patients had lower Hb levels,
lower ferritin levels, and more variability in red cell size. To
the best of our knowledge, there is no previous study that
identified this mutation in any population or database;
therefore, it is a novel variant.
Summarize English and Arabic text using the statistical algorithm and sorting sentences based on its importance
You can download the summary result with one of any available formats such as PDF,DOCX and TXT
ٌYou can share the summary link easily, we keep the summary on the website for future reference,except for private summaries.
We are working on adding new features to make summarization more easy and accurate
Showing kindness is a crucial human trait. When someone is facing hardship or difficulty, extending ...
بيان المهمة " توفير تعليم وتدريب عالي الجودة يحركه السوق ودعم ريادة الأعمال والبحث التطبيقي التعاوني...
مفهوم القيم في الفلسفة: يوجد اختلاف في النظر إلى القيم حسب المذاهب الفلسفية، وباعتبار المواضيع التي ...
الفصل 5: فورت كارون في الصباح بعد لقاءنا بالملك، عدت إلى فندقنا لاصطحاب روكسي، بينما بقيت زانوبا في...
ثانياً الأندلس : المراد بلفظ الأندلس اسبانيا الاسلامية بصفة عامة اطلق هذا اللفظ في بادىء الأمر على ش...
We then identify the enabling technologies for the introduced 6G services and outline a comprehensiv...
1. Exporting: - In this initial stage, the firm starts selling its products or services in foreign ...
إن الاعتدال والوسطية في المنهج الإسلامي من المسلمات المهمة للتعايش وبناء السلام، وعلى هذا المنوال نج...
وينبغـي أن يالحـظ أن العبـرة فـي وصـف المـادة بأنهـا سـامة أم ال، ليسـت بطبيعـة هـذه المـادة فـي ذات...
* Links surrounding window themes and frames the doors. * The connections between walls and foundat...
يشير الكتاب الى مسار المرض باعتباره محددا اساسيا في رحلة العلاج للمرضى منطلقا من تعريف أنسيلم ستراوس...
Laser Doppler Velocimetry: Principle: This technique measures the velocity of blood flow in retinal...