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Oral route of drug administration is the most appealing, convenient, significant and popular route for the delivery of drugs owing to ease of swallowing, self medication and most economic.They provide the advantages of combination therapy while reducing the number of prescriptions and the attendant administrative costs and improving patient compliance.Each layer may contain a different medicinal agent with varying release profiles Among these Bilayer tablet is new era for developing a combination of two or more active pharmaceutical ingredient in single dosage form, Promoting patient convenience and compliance.Each comes from a separate feed frame with individual weight control to form two or three-layered tablets, depending on the number of separate fills.Dual release tablet is a unit compressed tablet dosage form intended for oral application.


Original text

Oral route of drug administration is the most appealing, convenient, significant and popular route for the delivery of drugs owing to ease of swallowing, self medication and most economic.


Tablets are the most popular and preferred oral formulation available in the market because of its ease of manufacturing, convenience in administration, accurate dosing, stability compared with oral liquids and because it is more tamperproof than capsules.[1-4]


Modified release tablets are coated or uncoated tablet that contain special excipients or they are prepared by special procedures, or both, designed to modify the rate, place or time of release of the active substance(s).[5]


Layered tablets, type of modified release, prepared by compressing several different granulations fed into a die in succession, one on top of another, in layers.
Each comes from a separate feed frame with individual weight control to form two or three-layered tablets, depending on the number of separate fills.


Each layer may contain a different medicinal agent with varying release profiles
Among these Bilayer tablet is new era for developing a combination of two or more active pharmaceutical ingredient in single dosage form, Promoting patient convenience and compliance.


Dual release tablet is a unit compressed tablet dosage form intended for oral application. It contains 2 layers in which 1 layer having conventional or immediate release part of single or multiple actives; another layer is sustained or controlled release part of single or multiple actives.[7]


Combination products-also known as fixed dose combinations are combinations of two or more active drugs produced in a single dosage form. They provide the advantages of combination therapy while reducing the number of prescriptions and the attendant administrative costs and improving patient compliance.


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