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Treatment of excess acid Excess acid production can almost always be controlled.These are effective medicines for controlling acid production in Zollinger-Ellison syndrome.Proton pump inhibitors are powerful acid-reducing medicines.Medicines known as proton pump inhibitors are the first line of treatment.

Treatment of excess acid
Excess acid production can almost always be controlled. Medicines known as proton pump inhibitors are the first line of treatment. These are effective medicines for controlling acid production in Zollinger-Ellison syndrome.

Proton pump inhibitors are powerful acid-reducing medicines. They work by blocking the action of the tiny "pumps" within acid-secreting cells. Commonly prescribed medicines include lansoprazole (Prevacid), omeprazole (Prilosec, Zegerid), pantoprazole (Protonix), rabeprazole (Aciphex) and esomeprazole (Nexium).

Long-term use of prescription proton pump inhibitors has been associated with an increased risk of fractures of the hip, wrist and spine. People age 50 and older are at higher risk. However, this risk is small and should be weighed against their acid-blocking benefits.

Octreotide (Sandostatin), a medicine similar to the hormone somatostatin, may counteract the effects of gastrin and be helpful for some people.