Lakhasly

2.Part per million (ppm) is the unit that chemical shiVs were reported in. High resolu8on mass spectra HRMS were recorded at the Bioanaly8cal Mass Spectrometry Facility, Mark Wainwright Analy8cal Centre, The University of New South Wales UNSW, Sydney, Australia using Orbitrap LTQ XL ion trap MS in posi8ve ion mode via electrospray ioniza8on (ESI) source.The reac8ons progress was performed and monitored by thin layer chromatography u8lized by TLC plates of Merck aluminum-backed silica 60 F254 (0.2 mm) and the spots were visualized by alkaline KMnO4 staining solu8ons.Outstanding solvents peaks were used to calibrate 1H NMR spectra.Shimadzu FTIR spectrometer was used to collect IR spectra.

2. EXPERIMENTALWORK 2.1. Materials and instruments
   All chemicals and solvents were bought from commercial chemicals’ sellers, and they were used immediately without further purifica8on. All reac8ons were cleaned and dried in oven-dried glassware except stated otherwise. The reac8ons progress was performed and monitored by thin layer chromatography u8lized by TLC plates of Merck aluminum-backed silica 60 F254 (0.2 mm) and the spots were visualized by alkaline KMnO4 staining solu8ons. In the column chromatography, silica gel 60‒120 mesh was u8lized as sta8onary phase and the specified elu8ng solvents were used as mobile phase. Stanford Research System Op8melt automated mel8ng point apparatus was used to measure the mel8ng points. Shimadzu FTIR spectrometer was used to collect IR spectra. 1D NMR spectra were recorded at 298 K (± 1 K) using Bruker Advance III, 600 MHz instruments, Nuclear Magne8c Resonance Facility, Mark Wainwright Analy8cal Centre, The University of New South Wales UNSW, Sydney, Australia. Outstanding solvents peaks were used to calibrate 1H NMR spectra. Part per million (ppm) is the unit that chemical shiVs were reported in. High resolu8on mass spectra HRMS were recorded at the Bioanaly8cal Mass Spectrometry Facility, Mark Wainwright Analy8cal Centre, The University of New South Wales UNSW, Sydney, Australia using Orbitrap LTQ XL ion trap MS in posi8ve ion mode via electrospray ioniza8on (ESI) source.