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The traditional lobule is the most common description of a lobule, and you've probably heard of it. It's made up of hexagonal hepatocyte plates that are stacked on top of one another.In humans, connective tissue surrounds the portal canals, although the interlobular quantity is quite little.A periportal zone (Space of Mall) exists between the connective tissue of the portal canals and the hepatocytes, where lymph is generated.As hepatocytes expand towards the perimeter, they form strips, like the spokes of a cartwheel.These portal canals are made up of portal triads that are surrounded by loose stromal connective tissue.
The traditional lobule is the most common description of a lobule, and you've probably heard of it. It's made up of hexagonal hepatocyte plates that are stacked on top of one another. Within each plate, hepatocytes expand outwards from a central vein. As hepatocytes expand towards the perimeter, they form strips, like the spokes of a cartwheel. Between the hepatocyte strips, hepatic sinusoids drain into the main vein.
There is one portal canal at each corner of each hexagonal classic lobule, for a total of six portal canals.
These portal canals are made up of portal triads that are surrounded by loose stromal connective tissue. A periportal zone (Space of Mall) exists between the connective tissue of the portal canals and the hepatocytes, where lymph is generated.
In humans, connective tissue surrounds the portal canals, although the interlobular quantity is quite little. As a result, routine histological visualizations of the typical lobule can be difficult.
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