Lakhasly

Online English Summarizer tool, free and accurate!

Summarize result (50%)

Human hearing loss is a common neurosensory disorder about which many basic research and clinically relevant questions are unresolved. This review on hereditary deafness focuses on three examples considered at first glance to be uncomplicated, however, upon inspection, are enigmatic and ripe for future research efforts. The three examples of clinical and genetic complexities are drawn from studies of (1) Pendred syndrome/DFNB4 (PDS, OMIM 274600), (2) Perrault syndrome (deafness and infertility) due to mutations of CLPP (PRTLS3, OMIM 614129), and (3) the unexplained extensive clinical variability associated with TBC1D24 mutations. At present, it is unknown how different mutations of TBC1D24 cause nonsyndromic deafness (DFNB86, OMIM 614617), epilepsy (OMIM 605021), epilepsy with deafness, or DOORS syndrome (OMIM 220500) that is characterized by deafness, onychodystrophy (alteration of toenail or fingernail morphology), osteodystrophy (defective development of bone), intellectual disability and seizure


Original text

Human hearing loss is a common neurosensory disorder about which many basic research and clinically relevant questions are unresolved. This review on hereditary deafness focuses on three examples considered at first glance to be uncomplicated, however, upon inspection, are enigmatic and ripe for future research efforts. The three examples of clinical and genetic complexities are drawn from studies of (1) Pendred syndrome/DFNB4 (PDS, OMIM 274600), (2) Perrault syndrome (deafness and infertility) due to mutations of CLPP (PRTLS3, OMIM 614129), and (3) the unexplained extensive clinical variability associated with TBC1D24 mutations. At present, it is unknown how different mutations of TBC1D24 cause nonsyndromic deafness (DFNB86, OMIM 614617), epilepsy (OMIM 605021), epilepsy with deafness, or DOORS syndrome (OMIM 220500) that is characterized by deafness, onychodystrophy (alteration of toenail or fingernail morphology), osteodystrophy (defective development of bone), intellectual disability and seizure


Summarize English and Arabic text online

Summarize text automatically

Summarize English and Arabic text using the statistical algorithm and sorting sentences based on its importance

Download Summary

You can download the summary result with one of any available formats such as PDF,DOCX and TXT

Permanent URL

ٌYou can share the summary link easily, we keep the summary on the website for future reference,except for private summaries.

Other Features

We are working on adding new features to make summarization more easy and accurate


Latest summaries

) قرار الاستثما...

) قرار الاستثمار هو قرار الذي يهدف إلى تحديد مبلغ الأموال التي ستستثمر،وكذا اختيار نوع الأصول التي ت...

إن عملية جمع ال...

إن عملية جمع البيانات من مصادرها التاريخية أو الوثائقية كحصيلة لنشاط العديد من المؤسسات والشركات وال...

العوامل مسببات ...

العوامل مسببات الامراض الاخرى وكما يلي: ويلوث الكلوستريديام التربة والماء والنبات وعبر ذلك الأغذية و...

الشبكات الاجتما...

الشبكات الاجتماعية وسيله رائعه لبناء الوعي بعلامتك التجاريه وجذب المزيد من العملاء ولكن يجب عليك أن ...

رجو من جميع متا...

رجو من جميع متابعين والمشاهدين الاشتراك في القناة وتفعيل الجرس من اجل ان تعم الفائدة على الجميع. سات...

تسجيل الدخول ر...

تسجيل الدخول رياضة ألونسو يرفض تدريب بايرن ميونخ ويُبعد نفسه عن ليفربول تقارير إعلامية تتحدث عن رغ...

Experimental in...

Experimental investigations were conducted to examine the influence of surface enhancement on crysta...

الموسيقي القومي...

الموسيقي القومية Music Country : حركة مكسيقية ظيرت في أكائؿ القرف التاسع عشر ارتبطت فى البداية بحركا...

تشير الموجة الن...

تشير الموجة النسوية الأولى إلى نشاطات الحركة النسوية الممتدة خلال القرن الثامن عشر. والتي جاءت كاستج...

Digitalization ...

Digitalization affects international trade on many levels, by transforming the way in which goods a...

In telecommunic...

In telecommunications and computer networking, connection-oriented communication is a communication ...

١ - أَن هَذِه ا...

١ - أَن هَذِه الْمذَاهب الْأَرْبَعَة الْمُدَوَّنَة قد اجْتمعت الْأمة أَو من يعْتد بِهِ مِنْهَا على ج...