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Side Effects ?Patients with recent neurologic symptoms due to vascular insufficiency or evidence of severe cerebral vascular disease should not be considered candidates for dipyridamole stress testing.Acute neurologic events (stroke, transient ischemic attack) have been reported to occur in association with dipy ridamole infusion.Atrioventricular (AV) block occurs at a lower frequency than is observed with adenosine and regadenoson.Acute MI and cardiac death have rarely been associated with dipyridamole infusion.Inhaled bronchodilators may be required.??????

Side Effects
● Adverse effects occur in 40–50% of patients who receive dipyridamole infusion. Most effects are self‐limiting, and serious side effects are rare.
● Non‐cardiac side effects such as headache, flushing, dizziness, and gastrointestinal upset are frequent.
● Chest pain occurs in 10–25% of patients receiving dipyridamole. It is an insensitive marker of significant CAD.
● Atrioventricular (AV) block occurs at a lower frequency than is observed with adenosine and regadenoson.
● Acute MI and cardiac death have rarely been associated with dipyridamole infusion. ● Acute bronchospasm is a serious side effect which requires immediate therapy. In this situation, the dipyridamole infusion should be immediately terminated, and IV aminophylline (75–250 mg) should be administered. Inhaled bronchodilators may be required.
● Acute neurologic events (stroke, transient ischemic attack) have been reported to occur in association with dipy ridamole infusion. Patients with recent neurologic symptoms due to vascular insufficiency or evidence of severe cerebral vascular disease should not be considered candidates for dipyridamole stress testing.