لخّصلي

The bioreactor's main purpose is to provide a suitable and regulated environment for cell growth and product production.The scale-up offers the appropriate mass transfer rates while keeping in mind that scale-up is usually limited by oxygen supply and carbon dioxide removal, especially at extremely high cell densities.The design and mode of running a bioreactor should fulfill the requirements of output and specified process variables to generate higher quality products consistently and cost-effectively.Scale-up criteria are primarily concerned with reactor geometry, impeller speed, and aeration rate.oEasy to maintain and adjust various organisms for the specific reaction in the reactor.

The bioreactor's main purpose is to provide a suitable and regulated environment for cell growth and product production. The design and mode of running a bioreactor should fulfill the requirements of output and specified process variables to generate higher quality products consistently and cost-effectively. Several things must be considered in the building of a bioreactor in this fashion such as geometry, temperature, pH, illumination (when applicable), sterility, aeration and mixing systems (when necessary), low energy usage, as well as the right size and material . Scale-up criteria are primarily concerned with reactor geometry, impeller speed, and aeration rate. The scale-up offers the appropriate mass transfer rates while keeping in mind that scale-up is usually limited by oxygen supply and carbon dioxide removal, especially at extremely high cell densities. Therefore, bioreactors must meet certain requirements :
•Easy to monitor and/or control reaction parameters

•To operate reliably for days or even weeks to maintain microorganism growth

•To maintain aseptic conditions for long periods and cell retention

•To meet the requirement of productivity and yield in a cost-effective manner.

•Easy to maintain and adjust various organisms for the specific reaction in the reactor.