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Summarize result (51%)

When a medication is crushed, it may become more vulnerable to contamination by bacteria or other substances.Changes in the release of the active ingredient.Additionally, it destroys the tablet coating, making the crushed powder more susceptible to environmental factors, such as moisture from the air, that can hasten drug degradation, some tablets are long-acting formulations that are slowly released into the body and can last for up to 24 hours.crushing tablets or opening capsules that are taken orally, when it is not prescribed, can affect the efficacy of a treatment, or even cause an adverse event.Modification of absorption (enteric-coated tablets).Which tablets should never be crushed?Disadvantages:
1.2.3.4.5.6.1.2.3.4.5.6.


Original text

When a medication is crushed, it may become more vulnerable to contamination by bacteria or other substances.
crushing tablets or opening capsules that are taken orally, when it is not prescribed, can affect the efficacy of a treatment, or even cause an adverse event.
Additionally, it destroys the tablet coating, making the crushed powder more susceptible to environmental factors, such as moisture from the air, that can hasten drug degradation, some tablets are long-acting formulations that are slowly released into the body and can last for up to 24 hours. Crushing these types of tablets would eliminate the long-acting properties by causing the medication to be absorbed all at once.


Disadvantages:



  1. Loss of drug stability.

  2. Dosing error.

  3. Changes in the release of the active ingredient.

  4. Modification of absorption (enteric-coated tablets).

  5. Change in its effects.

  6. Risk in handling (they can be dispersed in the air and breathed by the person handling them).


Which tablets should never be crushed?



  1. Designed to have controlled release.

  2. Coated for protection or taste.

  3. Dissolvable.

  4. Liquid-filled gel capsules.

  5. Hazardous or irritants.

  6. Intended for a small therapeutic window.


A good option to avoid crushing medication is to look for other dosage forms. These alternatives can make treatment easier without having to manipulate pills. This way, you can avoid the risks we mentioned.


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