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which may cause recurring cold sores, and human alphaherpesvirus 2 (HHV-2), the more dangerous strain of genital herpes, result in lifelong infection.HHV-1 is transmitted mainly by oralto-oral contact and causes infection in or around the mouth (oral herpes).Furthermore, it has been shown that HHV-2 infection can cause an increased risk of being infected with human immunodeficiency virus (HIV) [6].Picornaviruses are positive-sense, single-stranded RNA viruses with small non-envelop
which may cause recurring cold sores, and human alphaherpesvirus 2 (HHV-2), the more dangerous strain of genital herpes, result
in lifelong infection. According to the World Health Organization
(WHO) an estimated 66.6 % of the world's population aged 0 to 49
had HHV-1 infection in 2016. HHV-1 is transmitted mainly by oralto-oral contact and causes infection in or around the mouth (oral
herpes). However, HHV-1 can also be transmitted through oralgenital contact during oral sex, which can cause genital HHV-1.
Furthermore, it has been shown that HHV-2 infection can cause
an increased risk of being infected with human immunodeficiency
virus (HIV) [6].
Picornaviruses, which belong to one of the largest and most
important virus families, pose a serious threat to human health and
agriculture. They cause diseases such as poliomyelitis, hepatitis A,
and foot-and-mouth disease. Picornaviruses are positive-sense,
single-stranded RNA viruses with small non-envelop
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